ANTIBACTERIAL ACTIVITY DETERMINATION OF SOURSOP PEEL EXTRACT (ANONNA MURICATA Linn) AGAINST PROPIONICACTERIUM ACNE

PENENTUAN AKTIVITAS ANTIBAKTERI EKSTRAK KULIT SIRSAK (ANONNA MURICATA Linn) TERHADAP PROPIONICACTERIUM ACNE

Authors

  • Kiki Mulkiya Yuliawati Universitas Islam Bandung
  • Yani Lukmayani Universitas Islam Bandung
  • Irene Yuliani Trinita Universitas Islam Bandung

DOI:

https://doi.org/10.29313/jiff.v7i1.3175

Keywords:

soursop peel, antibacterial acne, bacteriostatic

Abstract

The use of antibiotics for treatment, including acne treatment, has the potential to cause resistance. Therefore, acne treatment can be done using medicinal plants, in this case is soursop skin which considered as waste. This study aims to determine the antibacterial activity of soursop peel extract against the acne-causing bacteria Propionibacterium acne. Soursop peel extract was made using the Ultrasonic Assisted Extraction (UAE) method at a frequency of 50 Hz for 45 minutes. Antibacterial activity testing was carried out using the agar diffusion method using wells, at concentrations of 0.25%, 0.5%, 1%, 2%, 4% and 8%. Meanwhile, the determination of antibacterial activity was carried out using the turbidimetric method using Uv-Vis spectrophotometry. From the extraction process, the extract yield was 21.26%. Antibacterial activity testing showed that the MIC value of the test extract against P. acne bacteria was 1% and was bacteriostatic.

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Published

20-02-2024

How to Cite

Mulkiya Yuliawati, K., Lukmayani , Y., & Yuliani Trinita, I. (2024). ANTIBACTERIAL ACTIVITY DETERMINATION OF SOURSOP PEEL EXTRACT (ANONNA MURICATA Linn) AGAINST PROPIONICACTERIUM ACNE: PENENTUAN AKTIVITAS ANTIBAKTERI EKSTRAK KULIT SIRSAK (ANONNA MURICATA Linn) TERHADAP PROPIONICACTERIUM ACNE. Jurnal Ilmiah Farmasi Farmasyifa, 7(1), 57–66. https://doi.org/10.29313/jiff.v7i1.3175