OPTIMASI LOTION EKSTRAK WORTEL DAN KULIT JERUK NIPIS: OPTIMASI LOTION EKSTRAK WORTEL DAN KULIT JERUK NIPIS

WAHYUNITA SARI; Definingsih Yuliastuti; Malikhatul Munifah

doi:10.29313/jiff.v7i1.2849

Authors

WAHYUNITA SARI Stikes Serulingmas Cilacap
Definingsih Yuliastuti Poltekes Kemenkes Surakarta
Malikhatul Munifah STIKES Serulingmas Cilacap

DOI:

https://doi.org/10.29313/jiff.v7i1.2849

Keywords:

Lime peel, Lotion, Optimized, Simplex Lattice Design, Carrot

Abstract

Excessive sun exposure can cause sunburn, premature aging and skin cancer. Carrot and lime peel are plants that have natural sun protection activity in the presence of β-carotene and flavonoids. This study aims to determine the most optimum lotion formulation from carrot extract and lime peel based on the simplex lattice design method, namely, various differences in the amount of ingredient composition where the total amount of ingredients is made the same. Lotion from carrot extract and lime peel was made with a ratio of FI (12.5% lime peel : 0% carrot), FII (6.25% lime peel : 6.25% carrot), FIII (0% lime peel : 12.5% carrot) with the total amount of ingredients is the same. Carrot extract lotion and lime peel (FI, FII, FIII) have a pH that complies with the requirements, namely, 7.26 – 7.43 with antioxidant activity ranging from 344.39 ppm – 525.68 ppm. FI lotion (6.66) has a greater SPF lotion value compared to FII (3.46) and FIII (1.31). The most optimum formulation of carrot extract lotion and lime peel based on normality calculations (pH, antioxidants and SPF values), namely, FI (12.5% lime peel: 0% carrot).

References

Ardyanti, N. K. N. T., Suhendra, L., & Ganda Puta, G. P. (2020). Pengaruh Ukuran Partikel dan Lama Maserasi terhadap Karakteristik Ekstrak Virgin Coconut Oil Wortel (Daucus carota L.) sebagai Pewarna Alami. Jurnal Rekayasa Dan Manajemen Agroindustri, 8(3), 423. https://doi.org/10.24843/jrma.2020.v08.i03.p11

Auliasari, N., Najihudin, A., & Restuny, E. (2019). UTILIZATION OF LIME SKIN WASTE ( Citrus aurantifolia ) IN GEL FORMULAS AS ANTI-WRINKLE. Jurnal Ilmiah Farmako Bahari, 10(2), 171–182.

Bolton, S. (1997). Pharmaceutical Statistics and Clinical Applicatio. rd 3 edision. (3 ed.). Marcel Dekker Inc.

Daud, N. S., Daud, N. S., Ode, L., & Al, Z. (2016). FORMULASI LOTION TABIR SURYA EKSTRAK ETANOL BERAS MERAH ( Oryza nivara ). jurnal ilmiah ibnu sina, 1(September 2016), 143–150.

Depkes RI. (2017). Farmakope Herbal Indonesia. In Departemen Kesehatan Indonesia.

Dewi, B., & Wirahmi, N. (2019). Formulasi Lotion Ekstrak Wortel (Daucus Carota L) Metode Maserasi. Jurnal Ilmiah Pharmacy, 6(1).

Hajrin, W., & Juliantoni, Y. (2019). Formulasi Lotion Esktrak Etanolik Herba Ashitaba ( Angelica Keiskei ) sebagai Penangkal Radikal Bebas. 8(2), 5–8.

Kalsum. (2019). Uji Aktivitas Ekstrak Etanol Umbi Wortel (Daucus carota L.) Sebagai Antifungi Terhadap Pertumbuhan Candida albicans. Journal Binahusada, 8(September).

Lidia, Amalia, K., & Vebriola, F. (2018). Formulasi Gel Ekstrak Buah Tomat Dan Benzofenon Serta Uji Nilai SPF. Jurnal Penelitian Farmasi Indonesia, 2, 42–49.

Pandanwangi, Bachtiar, A., & Firmansyah, D. (2018). Uji Aktivitas Antioksidan Krim Kombinasi Ekstrak Daun Jambu Biji (Psidium guajava L.) Dan Ekstrak Umbi Wortel (Daucus carota L.) Dengan Menggunakan Metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Medical Sains: Junal Ilmiah Kefarmasian, 3(1), 31–42. https://doi.org/10.37874/ms.v3i1.62

Pertiwi, R. D., Yari, C. E., & Putra, N. F. (2017). UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL LIMBAH KULIT BUAH APEL (Malus domestica Borkh.) TERHADAP RADIKAL BEBAS DPPH (2,2-Diphenyl-1-Picrylhydrazil). Jurnal Ilmiah Manuntung, 2(1), 81. https://doi.org/10.51352/jim.v2i1.51

Rabima, & Marshall. (2017). Uji Stabilitas Formulasi Sediaan Krim Antioksidan Ekstrak Etanol 70% Dari Biji Melinjo (Gnetum gnemon L.). Indonesia Research Pharmaceutical Journal, 2(1), 107–121.

Rabima, & Pangaman, S. D. (2020). FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN DARI SEDIAAN MASKER PEEL-OFF EKSTRAK UMBI WORTEL VARIETAS CHANTENAY (Daucus carota L.). indonesia Natural Research Journal, 5(2), 135–148.

Tamrin, M. (2022). Studi literatur Penetapan Rendemen Ekstrak Etanol Myrtaceae Menggunakan Metode Maserasi. Stiksam.

Ulfah, M., & Sumantri, S. (2014). UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOLIK KULIT BUAH JERUK NIPIS (Citrus aurantifolia) DENGAN METODE DPPH (1,1-difenil-2- pikrilhidrazil). e-Publikasi Fakultas Farmasi, 11(2), 9–17.

Widiyanto, A. (2007). Isolasi dan Identifikasi Flavonoid dari Fraksi Eter Perasan Daging Buah Makuta Dewa. Skripsi.

Widyawati, E., Ayuningtyas, N. D., & Pitasari, A. P. (2019). Penentuan Nilai SPF Ekstrak Dan Losio Tabir Surya Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Dengan Metode Spektrofotometri UV-VIS. Jurnal Riset Kefarmasian Indonesia, 1(3), 189–202.